United States securities and exchange commission logo June 22, 2023 David Jin, M.D., Ph.D. Chief Executive Officer Avalon GloboCare Corp. 4400 Route 9 South, Suite 3100 Freehold, NJ 07728 Re: Avalon GloboCare Corp. Registration Statement on Form S-3 Filed June 16, 2023 File No. 333-272736 Dear David Jin: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tyler Howes at 202-551-3370 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Steven M. Skolnick, Esq.